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Clinical Research Department

Carolina Health Specialists Clinical Research Department is a multi-specialty research department that conducts Phase II, III, and IV trials. We are dedicated to providing patients the opportunity to participate in clinical trials with up-to-date treatments, many of which offer new medications to treat a variety of conditions.

Current Studies Include:

Novo Nordisk NN9924-4257 Pioneer 7: 
Efficacy and Safety of Oral Semaglutide using a Flexible Dose adjustment based on Clinical Evaluation versus Sitagliptin in Subjects with Type 2 Diabetes Mellitus (CLOSED TO SCREENING)

Novo Nordisk NN9924-4221- Pioneer 6: A trial investigating the cardiovascular safety of oral semaglutide in subjects with Type  2 Diabetes Mellitus

GSK GLP116174 Harmony Outcomes: A long term, randomized, double blind, placebo-controlled study to determine the effect of albiglutide, when added to standard blood glucose lowering therapies, on major cardiovascular events in patients with Type 2 diabetes Mellitus.(CLOSED TO SCREENING)

Novo Nordisk NN2211-4315: Liraglutide versus placebo as add-on to SGLT2 inhibitors. 

Sanofi Aventis- EFC11570 - Odyssey Outcomes: a randomized, double-blind, Placebo controlled, Parallel-group study to evaluate the effect of alirocumab on the Occurrence of Cardiovascular Events in Patients who have recently experienced an Acute Coronary Syndrome (CLOSED TO SCREENING)

Boehringer Ingerheim- BI1245.72- EASE 3: 
A Phase 3, randomized, double blind, placebo-controlled, parallel group, efficacy, safety and tolerability trial of one daily, oral dosed of Emagliflozin as Adjunctive to Insulin Therapy over 26-weeks in patients with Type 1 Diabetes Mellitus. (CLOSED TO SCREENING)

Comparative and Pragmatic Study of Simponi Aria versus Remicade in Rheumatoid Arthritis: An Infusion Study for those with Rheumatoid Arthritis. (Janssen Research & Development)

Prospective Outcomes Study: Vectra DA Guided Care Compared to Usual Care: A study for those with Rheumatoid Arthritis. (Crescendo Bioscience)

Sanofi EFC14875: A randomized, double-blind, placebo-controlled, Parallel-group, multicenter study to demonstrate the effects of Sotagliflozin on cardiovascular and renal events in patients with type 2 Diabetes, cardiovascular risk factors and moderately impaired renal function.

UAB (University of Alabama Birmingham) Verve: The safety and effectiveness of the VaricElla zosteR VaccinE (VERVE) in anti-TNF users.

BMS (Bristol-Myers Squibb) IM101-686: An Observational Study: The value of Orencia in rapidly progressing Rheumatoid Arthritis: A Chart Review study.


Mary Green - Clinical Research Coordinator
Irena Ross, CMA/CCRC - Certified Clinical Research Coordinator


If you have been diagnosed with any of the above mentioned health conditions including Rheumatoid and Type 1 or 2 Diabetes and are interested in learning more about available clinical studies, please contact us at

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